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Table of Contents

Overview
Patient Presents
History
Physical Examination
Laboratory Findings
Differential Diagnosis
Etiology
Pathophysiology
Hospital Progress Report
Types of TTP
Interfering Substances
Treatment and Management
Morbidity / Mortality
Quiz
References

Authors:

Ihab Abumuhor, BS, MT (ASCP)

Ellen Hope Kearns, MS, SH(ASCP)H

Division of Health Sciences, School of Health, California State University Dominguez Hills, Carson, CA
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Thrombotic Thrombocytopenic Purpura

Quiz


1. TTP is characterized by:
A. Elevated serum LDH
B. Low platelets count
C. Increased reticulocyte count
D. Decrease: platelet, reticulocyte count, LDH
E. A, B and C

2. Which of the following is contraindicated in the management of severe TTP?
A. Platelet transfusion
B. Plasmapheresis
C. Splenectomy
D. Cryoprecipitate depleted plasma

3. Which of the following is not a hallmark of TTP?
A. Microangiopathic hemolytic anemia
B. Central nervous system involvement
C. Thrombocytopenia
D. Peak incidence at age 40
E. None of the above

4. Distinguish between TTP, ITP, and HUS?
[Answer to # 4]


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Next: References

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Last Update: August 29 2006